Fridzon started his professional career in the Russian team Standart Toliatti back in 2001, and stayed with them until the end of 2003–04 season.

He then moved to the prominent Moscow-based team Khimki. With Khimki, he won the Russian Cup in 2007 and the VTB United League in 2011, while also being the VTB United League Final Four MVP. Year later, he won the EuroCup, second-tier continental championship, thus way giving his team a spot in the 2012–13 Euroleague, after year of absence. In the 2012–13 season, he averaged career-high 11.4 points and 2.2 rebounds in 24 EuroLeague games. However, Khimki didn't win any trophy that season.

On June 13, 2013, Fridzon signed a two-year contract with the option for third season with the Russian team CSKA Moscow. In his first season with CSKA, in the EuroLeague, he averaged 7.5 points, 1.5 rebounds and 1.1 assists over 31 games.

In 2014–15 season, CSKA Moscow has managed to advance to the EuroLeague Final Four for the fourth straight season, after eliminating Panathinaikos for the second straight season in the quarter-final series with a 3–1 series win. However, in the EuroLeague semifinal game, despite being dubbed by media as an absolute favorite to advance, CSKA once again lost to Olympiacos. The final score was 70–68, after a great Olympiacos comeback in 4th quarter, led by Vassilis Spanoulis. CSKA Moscow eventually won the EuroLeague third place game after defeating Fenerbahçe by a score of 86–80.[4] Fridzon had nearly the same season, statistically speaking, like his first season with the club, averaging 7.8 points, 2.3 rebounds and 1.4 assists per game, over 23 games played in the EuroLeague. CSKA Moscow finished the season by winning the VTB United League, after eliminating Khimki with a 3–0 sweep in the league's finals series.

On June 16, 2016, he re-signed with the team, on a new two-year contract, with the option of another season.